Psychiatric Aspects Of MDMA (3,4-Methylenedioxymethamphetamine): The ‘Diathesis-Stress’ Explanatory Model

Psychiatric Aspects Of MDMA (3,4-Methylenedioxymethamphetamine): The ‘Diathesis-Stress’ Explanatory Model

The first individual case studies were published around 1990-1994, soon after MDMA was used for recreational purposes. In a comprehensive review of this case study literature, around one third of individuals had premorbid problems, while most cases did not have prior vulnerability factors [3]. Larger population surveys have found that recreational Ecstasy use is associated with significantly ra...

Ecstasy: 3,4-methylenedioxymethamphetamine (MDMA).

The crystal structure of 3,4-methylenedioxymethamphetamine [systematic name: N-methyl-1-[3,4-(methylenedioxy) phenyl]-2-aminopropane] hydrochloride, C11H15NO2.HCl, also known as 'ecstasy' or MDMA, has been determined by X-ray diffraction.

3,4-methylenedioxymethamphetamine (MDMA): current perspectives

Ecstasy is a widely used recreational drug that usually consists primarily of 3,4-methylenedioxymethamphetamine (MDMA). Most ecstasy users consume other substances as well, which complicates the interpretation of research in this field. The positively rated effects of MDMA consumption include euphoria, arousal, enhanced mood, increased sociability, and heightened perceptions; some common advers...

The Stress-Diathesis Model of Suicidal Behaviour

Methylenedioxymethamphetamine (MDMA, ‘Ecstasy’): Neurodegeneration versus Neuromodulation

The amphetamine analogue 3,4-methylenedioxymethamphetamine (MDMA, ‘ecstasy’) is widely abused as a recreational drug due to its unique psychological effects. Of interest, MDMA causes long-lasting deficits in neurochemical and histological markers of the serotonergic neurons in the brain of different animal species. Such deficits include the decline in the activity of tryptophan hydroxylase in p...